Catalog 2014-16

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The Genomics Leadership Initiative at Juniata College

The Genomics Leadership Initiative at Juniata College has been funded by the Howard Hughes Medical Institute and National Science Foundation. The initiative seeks to achieve its goal by developing a genomics certificate program, a leadership module, and student summer research experiences.

GENOMICS CERTIFICATE PROGRAM:

Comprised of seven courses, the genomics certificate addresses both the science and the broader ethical, legal and social implications (ELSI) surrounding progress and discoveries in the field of genomics. The ethical, legal and social issues surrounding advances in genomics provides a strong focus for practicing a breadth of knowledge and skills; the understanding of the scientific foundation of genomics provides the focus for developing an interdisciplinary base and cross disciplinary understanding of the life sciences in an era of “big data”. To help support this part of the program the grant has also funded an ELSI faculty development workshop, a seminar series, stipends for faculty developing new or revised classes, and stipends for faculty to formally assess the learning gains of students as a result of programmatic activities.

What is a certificate?

In general, an undergraduate certificate provides an interdisciplinary curriculum that is not available within any single academic unit. A certificate offers the possibility of a more cohesive general education experience oriented around a theme and taught by faculty who work together as a group on an ongoing basis and have common inter-departmental learning objectives and assessments. The awarding of the certificate is noted on the student’s transcript.

Who is this certificate for?

Students intending to pursue careers in biological research and medicine are the primary target. However, students interested in careers in public policy, public health, law, and business will gain by developing similar competencies.

Why should a student get this certificate?

As cost of a human genome approaches $1000, appreciation of both the science and the ethical, legal, and societal implications of genomics has become an increasingly pressing issue. Design of the certificate was based on recommendations from a joint document between the Howard Hughes Medical Institute (HHMI) and Association of American Medical Colleges (AAMC) entitled, “Scientific Foundations for Future Physicians.” This report emphasized the importance of integrative scientific approaches, scientific reasoning, intellectual curiosity, communication and decision making skills, adaptability, ethical principles, and understanding of patients as individuals and in a social context. HHMI has funded Juniata College to implement this certificate program.

Description and Goals of a Certificate in Genomics, Ethics, and Society

Comprised of seven courses, the certificate addresses both the science and the broader ethical, legal and social implications (ELSI) surrounding progress and discoveries in the field of genomics. No area of modern biology provides a more appropriate focus for combining the humanities and sciences than the ethical, social and legal implications (ELSI) of the human genome project and the evolution of the field of personalized medicine. The subject cannot be completely addressed without the input of specialists working across disciplinary boundaries. The ethical, legal and social issues surrounding advances in genomics provide a strong focus for practicing a breadth of knowledge and skills while understanding the acts of judgment and social contexts involved in the development and application of scientific knowledge; the understanding of the scientific foundation of genomics provides the focus for developing an interdisciplinary base and cross disciplinary understanding of the life sciences in an era of “big data”.

Learning objectives

Students who attain genomics certification will be able to:

Describe the basic concepts and principles of genomics.
Explain the scope of genomics from genes to society.
Integrate knowledge of the chemical, physical, mathematical and computational bases of genomics.
Explain the importance of the place of genomics in the human effort to understand natural phenomena, including its history and social impact.
Be able to make and justify ethical judgments about genomics research and its uses in medical practice and elsewhere.
Use the skills and interdisciplinary perspectives of the liberal arts in understanding trends in genomics and communicating them to academic peers and others.
Apply the process of science to questions in genomics.
Demonstrate an in-depth knowledge of a selected field in genomics.
Progress into a leadership role, working with experts and non-experts, with an awareness of the likely results of one's actions and an understanding of how results might differ in different settings and different cultures.

REQUIREMENTS

Core Courses: All students pursuing a genomics certificate must take four core courses required for a genomics certificate. Download the Genome Certificate Sheet to organize and plan your course of sudy.

1) Genomics, Ethics and Society (IC 203; Fall; MW 2-3:50PM; CWS prereq) A team-taught course that lays the foundations for interdisciplinary work on the ethical and social dimensions of genomics:.

2) A course covering basic molecular biology, genetics, and genomics:

Biology II BI 106; Fall; N division class; T/Th 9 to 10:20AM, or T/Th 1 to 2:20PM, Discussion Sections Weds 8 or 10AM; BI-105 CH-105 prereqs
Human Biology BI 109; Not for biology majors; Fall; N division class; MWF 9 to 9:55PM

3) At least three credits of statistics:

Biostatistics with lab BI 305, Fall; N and QS division class; T/TH 10:30 to 11:50AM; Lab M 1 to 2:55PM or 3 to 4:55; BI105 or ESS100 prereq
Environmetrics ESS 230; Spring N division and QS class; T/Th 10:30 to 11:55AM; Sophomore standing
Introductory Probability and Statistics MA 220, Fall MWF 10 to 10:55AM; Discussion T noon; Spring MWF 1 to 1:55PM, TH 2:30 to 3:25PM; QS and N division class, prereq MA130.

4) One course covering informatics and analysis of large data sets:

Information Discovery IM 241, Fall QS and S division class; T/TH 9 to 10:20AM; prereqs IT110 or IT111 or CS110 or Instructors Permission (Loren Rhodes)
Biological Sciences Research Methods (Lamendella, Buonaccorsi, and Keeney sections)
Even Spring Semesters (Buonaccorsi), N division class; MW 2 to 4:50PM; prereqs BI207 or Instructors Permission
Odd Fall Semesters (Lamendella), N division class; schedule TBA; prereqs BI207 or Instructors Permission
Even Fall Semesters (Keeney), N division class; schedule TBA; prereqs BI207 or Instructors Permission
Computer Science 110 section G only, Spring N class, MWF 8AM to 8:55AM
Unix CS 255U, 1 credit every semester, T 8AM, prereq Computer Science 110 or Instructors Permission (Loren Rhodes);

AND

Perl CS255P, 2 credits, Summer, prereq Computer Science 110 or Instructors Permission (Loren Rhodes), sophomore standing, self study

or

Python CS255Y, 2 credits, Summer, prereq Computer Science 110 or Instructors Permission (Loren Rhodes), sophomore standing, self study

Electives: In addition to the core courses, students must take at least three elective courses related to ELSI genomic themes:

Social History of Medicine History HS 211; Every Fall; May count as a either a CA, or an H or I division class. T/TH 1 to 2:20PM
Medieval Medicine: Health and Disease in the Middle Ages History HS 399, Every Spring. H division class. MW 11AM to 12:20PM
Doctors, Medicine and Literature Russian RU 299 01, Fall of odd numbered years. May count as a either a CA, or an H or I division class. T/TH 10:30 to 11:50PM, T Noon to 12:55pm.
Science and Human Values Philosophy PL 250, Spring of odd numbered years, H division class.
Moral Judgment Psychology 3XX, Every Summer online, S division class.
Leadership in the 21rst Century. Business EB 299, Odd Springs online (3 cr), S division class

AND Executive Leadership Business 199, 1 cr, Spring, 3PM, Weds.

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