Dr. Williams

Many students remain on campus over the summer to do research with Juniata faculty. We have had as many as 50 students doing paid summer research in the various departments. Many students also do research during the academic year, either for extracurricular experience or for credit. In addition, some students spend summers at other sites doing research. Recent students have been at federal labs at Oak Ridge and Argonne, academic labs at Harvard, Utah, Virginia, and Berkeley, and industrial labs such as Restek.

Most Juniata chemistry graduates do research at some point during their undergraduate careers, and many present their work at outside conferences. Juniata always has one of the largest contingents at the annual National Conference on Undergraduate Research, and each year a group of students and faculty attend the spring American Chemical Society meeting and present posters there.

 Recent Student Research 

  • Angela Wilkins '20, Isabella Weber '20, and Nicodemus Usry '19: "Poppy Seed Consumption and Associated Morphine Levels for Urine and Saliva Samples." 
  • Tyler Weigel '19: "Preparation of Chiral Aziridines Through a Copper-Catalyzed Asymmetric Reduction of 2H-Azirines." 
  • Katie Goerl '19: "Synthesis of 2-Pyridinecarbaldehyde N-Oxide." 
  • Michael Fox '19: "Synthesis of Polythiopene Nanoparticles for Astrochemistry Research." 
  • Jessica Zavadak '18: "Differential Gene Expression in Alzheimer's Disease Mouse Model." 
  • James McGettigan '18: "The Synthesis of Selectively Deuterated Tetra(benzyloxy)benzenes for Mass Spectrometry Studies." 

Current Faculty Research 

Dr. Ames

Research within the Ames lab focuses on utilizing methods and insight from a number of chemical sub-disciplines. Most projects require knowledge of the organic, inorganic, analytical, physical, and biochemical sub-disciplines. Students working within the group have been involved in organic synthesis, inorganic transition metal complexation, analytical electrochemical measurements, thin film materials analysis, quantum mechanical calculations of reaction mechanisms, and molecular dynamics simulations of biomolecules to name a few.

The major thrust of our research is the investigation of porphyrin molecules as catalysts – either for water oxidation, or for carbon dioxide reduction – both important topics relating to sustainable clean energy research.

Dr. Ames also has interest in the spectroscopy and reactivity of bioinorganic molecules and inorganic model complexes, as well as the characterization of radical enzyme intermediates.

In working with Dr. Ames, and other group members, it is the goal that student researchers will become full owners of their projects. Moving from the primary role of student to the role of colleague, an equal partner in the research being done. 

Dr. Baran

Our research is focused on the synthesis and characterization

of coordination compounds with applications as:BaranReserach1

1. catalysts in organic synthesis,

2. new magnetic materials, or

3. complexes with interesting biological properties.

We also study metal complexes in plant products, such as grape wine, and interactions between metallic ions and organic compounds found in plants.

A common feature for most of our projects is the implementation of aromatic amine N-oxides as organic ligands and building blocks for transition metal coordination compounds. Besides the use of some classical N-oxides, for example pyridine N-oxide or 1,10-phenanthroline N-oxide, we also synthesize new derivatives of N-oxides to fine-tune their chemical and physical properties. As far as for metals, mostly complexes with first row transition metals are explored.

Composition and structure of the organic ligands and inorganic coordination compounds are studied by spectroscopic methods and X-ray crystallography available in our department. We maintain collaborations on study of magnetic properties and biological activity of prepared complexes with other US institutions as well as international partners in Slovakia, Czech Republic, and Germany. Undergraduate students from our group present their research at various venues including the national ACS meetings and international conferences abroad. Our accomplishments have been published in peer-reviewed journal such as Inorganic Chemistry, Inorganica Chimica Acta, Acta Crystallographica and more publications are coming soon.     

A series of new polydentate Schiff base ligands containing pyridine N-oxide fragment(s), such as those shown below, were prepared in order to study Transition Metal Complexes for Catalysis in Organic Oxidations.


Ability of the N-oxide group to bridge between two metallic centers predetermines N-oxides to act as bridging ligands in the formation of multinuclear complexes. At the appropriate composition, some of these exhibit properties reminiscent of Single Molecule Magnets. In the case of ferromagnetic interactions between metallic centers, the overall effective magnetic moment adopts much bigger values than those in mononuclear complexes, predetermining such complexes to be studied for use as non-gadolinium based Magnetic Resonance Imaging Contrast Agents.

Purine N-oxides, such as guanine 3-N-oxide, we use as organic ligands in coordination compounds with potential Anticancer Activity.

Prevention of skin allergies caused by urushiol, an allergen found in Poison Ivy and several other plants, is studied using model compounds as well as urushiol itself. Interaction of urushiol with metallic salts shows promises to an effective prevention of the penetration of the urushiol through the skin to the blood stream.   

Some natural systems such as wine represent an extremely complex equilibrium of hundreds of organic compounds (sugars, alcohols, carboxylic acids, phenolics, esters, aldehydes, amines, …) interacting with dozens of metallic cations creating possibly thousands of coordination compounds. Our group is trying to open a door into this fascinating yet completely unmapped territory of Wine Chemistry.


Dr. Dries

Descriptive caption of photo goes here for assistive technologies
Dr. Dries

Our lab is interested in neurological diseases, particularly Alzheimer’s disease. We take a variety of approaches, ranging from enzymatic assays to microscopy. I believe that students learn best from one another. While I have weekly meetings with all students, I rely on the students to teach the various techniques to one another, further cementing their understanding in the lab. Undergraduate researchers have presented their work in a variety of ways, including at national meetings and as theses. For more information, please visit our lab webpage to learn who we are and what we do!

Dr. Hark

Descriptive caption of photo goes here for assistive technologies
Dr. Hark helping a student with her synthesis project

Our research group works on a variety of projects ranging from organic synthesis to laser-based analytical methodologies. We enjoy collaborations with international researchers (Germany, Spain, United Kingdom) and colleagues at US institutions (Smithsonian, US Army Corps of Engineers Cold Regions Research and Engineering Laboratory). Our research efforts are principally focused on three areas:

  • Application of analytical and imaging techniques to the study of cultural heritage objects.   We use non-destructive techniques such as Raman spectroscopy, X-ray fluorescence (XRF) spectroscopy, and infrared reflectography to identify pigments in various types of artworks such as Pennsylvania German fraktur (a folk art form), portrait miniatures (small watercolor paintings on ivory substrates that were especially popular in the later 18th and early 19th centuries), and an illuminated manuscript copy of the Bhagavad Gita.
  • Analysis of geomaterials and items of forensic interest using laser-induced breakdown spectroscopy (LIBS). Though LIBS is currently part of the suite of instruments on the Mars Curiosity rover we use it for more terrestrial applications including geochemical fingerprinting to determine the geographic origin of "conflicts minerals” (natural resources mined in areas characterized by conflict and human rights abuses), obsidian (of interest to archeologists who study the source of tools used by Neolithic people), carbonate minerals and garnets.  We use both laboratory-based instruments and handheld versions for these studies. Students are also analyzing gunshot residue and “white powders” (commonly encountered by first responders in hazmat situations).
  • Synthesis of isotopically labeled organic compounds and investigation of novel reactions. Selective placement of deuterium atoms on molecules of interest allow our collaborators to use mass spectrometry and LIBS to study the fragmentation patterns of small molecules. We also have discovered a couple of new synthetic reactions and are currently exploring the scope of the methodology.


Dr. Williams

Descriptive caption of photo goes here for assistive technologies
Dr. Williams helping students with the NMR

Inorganic metals are at work all around us, from the enzymes that function in biology to the magnets that power our cell phones to the catalysts that are used in chemical industry. The goal of research in our lab is to better understand how a metal ion’s environment affects its properties in order to better understand the roles that metals play in a variety of applications. To investigate this topic, students in the lab perform organic and inorganic synthesis and make use of a wide variety of analytical techniques. Undergraduate students working in the lab learn the value of collaboration and challenge themselves to solve difficult problems. Students also have the opportunity to present their research at a variety of on- and off-campus venues.


Dr. Yohn

Descriptive caption of photo goes here for assistive technologies
Collecting samples from Raystown Lake for Dr. Yohn

Chemistry doesn’t just happen in the laboratory – it happens all around us. Environmental geochemistry involves the integration of chemistry with biology, geology and physics to collect, interpret, and apply information about aquatic and terrestrial natural systems. Much of our work focuses on the local 28 mile long reservoir, Raystown Lake, including a long term monitoring program evaluating the health and trophic status of the lake, as well as investigating the relationship between nutrients and the spread of invasive aquatic plants. Students in this group combine field and lab work to answer specific applied questions about natural systems, as well as developing analytical techniques to quantify relevant chemicals such as chlorophyll or organic contaminants.